Abstract
Cancer is a collection of illnesses marked by unchecked cell division and proliferation. Genetic, environmental, and lifestyle factors are among the several causes of this condition, which can impact different body areas. Apart from this, Cancer is one of the leading causes of death globally; hence, the discovery of novel therapeutic medications is essential. The treatments which are now being used for cancer, like chemotherapy and radiotherapy, can cause disruption to many physiological processes, due to which the healthy cells and hair are damaged. The fauna of the sea contains low molecular weight peptides, so researchers around the world are working to utilize these natural faunas instead of the chemical pharmaceutical products, which have high side effects. Additionally, bioactive peptides from plants and animals have gained increased interest in recent years. Their modes of action and potential uses in the prevention and treatment of cancer, heart disease, and infectious diseases have drawn the attention of researchers. In this study, the anti-cancer potential of Litopenaeus vannamei extracts from Gwadar against human cancer cell lines was investigated. White shrimp extracts' cytotoxic effects on cancer cell lines were evaluated using the MTT assay. Our results demonstrated a dose-dependent increase in apoptosis and a significant reduction in cell viability when white shrimp extracts were administered to cancer cells. Based on the range of IC50 values, the extracts showed potential anti-cancer properties. The results imply that compounds found in white shrimp may have therapeutic uses in the management of cancer. This study contributes to the growing body of research indicating that compounds obtained from marine sources hold a promising source of anticancer medications.
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