Comparative analysis of Kidney Stones Collected from Male and Female Samples of Different Age Groups from Quetta City
DOI:
https://doi.org/10.31580/pjmls.v7i1.2991Keywords:
Cysteine, Etiopathogenesis, FTIR, Kidney stone, Nephrolithiasis Uric acid, Urinary calciumAbstract
Background: Kidney stone or Nephrolithiasis is a hard crystalline mineral. An infection with a multifactorial etiopathogenesis, kidney stone sickness might very well be caused by calcium stones, uric acid, struvite, or cysteine. Problems with crystallization promoters and inhibitors, or with stone metabolism and excretion, are the cause of most stones. Numerous risk factors, including as dietary practices, exposure to warm weather, and family history, have been demonstrated in epidemiological and clinical research to contribute to the development of illness and can only be diagnose by knowing its compositions. The aim of this study was to identify the kind and chemical composition of kidney stones in different age and gender of our community to guesstimate its relay on age and gender.
MethodS: The current research has done to examine the chemical type and composition of kidney stones in different age group which ranges from 20 to 46 plus years of different gender. A total of 13 kidney stone samples of males and females (7 samples were of male and 6 were of female) were collected to analyze for chemical composition by FTIR.
Results: Only one sample had magnesium ammonium phosphate (Struvite) while seven (7) samples were consisted of calcium oxalate + uric acid+ magnesium ammonium phosphate and the remaining five (5) were observed to contain calcium oxalate+ magnesium ammonium phosphate.
Conclusion: Gender wise contrast exposed that majority of those stones were collected from male patients as compared to females, as the observed ratio was (53.84%) and (46.14%) respectively. Age wise distribution showed that ages of patient ranged from 21 to 31 years, which may be attributed to the fact that older stone formers excrete less urinary calcium than their younger counterparts and may show defects in urinary inhibitors of crystallization.
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