The Role of H1 and H2 Blocker in Eradication of Gastrointestinal Malfunctioning
DOI:
https://doi.org/10.31580/pjmls.v2i1.987Keywords:
H1 ANDH2 BLOCKER histamineAbstract
Proton pumps releases acids in GIT which results in increased level of alkaline phosphates. The liver irritation by increased alkaline phosphates results in histamine disbalance. H1 ANDH2 BLOCKER acts as histamine controlling agents. The bacteria use their flagella to stick in stomach mucosal layer. For bacterial growth optimal conditions includes oxygen level b/w 5-15%, approx. CO2 5%, availability of some special amino acids, and 30-37°C temperature. Gastro intestinal Infections involve a spiral-shaped, gram-negative, micro bacterium. It was assumed that earlier no germ might survive in gastric acidic layer, therefore the possibility of microbial colonization of stomach actually was not considered. Thus, the bacterial microenvironment directly surrounds and neutralize the effects of gastric secretions which are corrosive to them and the pathogen escapes.
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