Investigating Anticancer Potential of Red Algae (Rhodophyceae) from Gwadar Sea Shore Research Article
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Cancer is one of the most dangerous diseases in the world due to its poor prognosis, negative treatment outcomes, and medication resistance. Nowadays, many chemical therapies and harsh techniques are used to cure cancer, which can affect the body's other healthy cells. For this reason, red algae are a potential treatment option. The red algae have a low calorie content and are high in antioxidants, polyunsaturated fatty acids, proteins, minerals, vitamins, and soluble dietary fibers. However, just like other plants, their nutrient contents are affected by outside variables like the season, environment, geographic location, and sampling conditions. The purpose of this study was to check the anticancer activity of red algae (Rhodophyceae) which were collected from the sea shore of Gwadar, Balochistan, Pakistan. Five grams of the powder algae was macerated by immersing it in fifty milliliters of solvent (methanol 100%, chloroform/methanol (3:2), and dichloromethane 100%) for seventy-two hours. Then the samples were filtered, and a rotary evaporator operating at low pressure at 30 to 35°C was used to dry out the resulting algae extracts. The Cancerous cells were used to check the anticancer potential of the extract obtained from red algae. MTT assay was used to check the anticancer activity. Results were calculated with the help of IC50 calculation, and from IC50 calculation, the percent viability of cells was obtained.
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