Targeted Probiotic Delivery via Bacteriophage-Resistant Capsules: A Novel Approach to Enhance Gut Health Review Article
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Abstract
Probiotics are live microorganisms that have beneficial health effects when taken. Because they may be harmed by gastrointestinal tract disorders, beneficial bacteria must be delivered through effective mechanisms in order to maximize their potential. By using bacteriophage-resistant capsules for targeted probiotic delivery, the study aims to investigate a novel approach to enhancing gut health. The review investigates how combining bacteriophage-resistant capsules with different encapsulation techniques can improve the survivability, specificity, and efficacy of probiotics in the GI tract. The study looks at phage-resistant capsules, complex interactions between phages and probiotics, and various encapsulation methods for bacteriophages and probiotics, including hydrogels, spray drying, liposomes, and microencapsulation. It concludes that by combining advanced encapsulation techniques with bacteriophage-resistant capsules, R-capsule technology can alter microbiota, treat illness, improve nutritional outcomes, extend the shelf life of probiotics, and create customized gut health regimens.
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