Exploring Serum Lipid Profile in Patients Diagnosed with Myocardial Infarction at Hayat Abad Medical Complex Peshawar

Abstract

Myocardial Infarction (MI) is a critical medical emergency requiring prompt diagnosis to ensure effective management and prevent life-threatening complications. Blood biomarkers play a vital role in predicting and mitigating the risk of MI. This study was conducted in the cardiology department of Hayatabad Medical Complex, Peshawar, to evaluate serum lipid profiles in MI patients. A total of 109 diagnosed MI patients were recruited through a non-probability convenient sampling method. Aseptic collection of 3–5 mL blood samples was performed, and the samples were processed at the tertiary healthcare facility. Serum was separated by centrifugation at 1000 revolutions per minute (RPM) for one minute. Lipid levels, including total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL-C), and very low-density lipoprotein cholesterol (VLDL-C), were measured using a COBAS analyzer. Statistical analysis revealed a predominance of male patients (63.3%) compared to females (36.7%), with the majority of cases observed in the age group of 51–60 years (29%). Dyslipidemia was a prominent finding, with elevated VLDL-C levels noted in 57.8% of patients, hypertriglyceridemia in 33.9%, and significantly reduced HDL levels in 46.8%. Additionally, 11.9% of patients exhibited elevated LDL cholesterol, while hypercholesterolemia was observed in 2.8% of cases. These findings underscore the significant role of dyslipidemia in predisposing individuals to MI. Early detection and management of lipid abnormalities are essential to prevent the progression to myocardial infarction and reduce associated morbidity and mortality.