Antimicrobial Resistance Profile of Enterobacteriaceae Isolated from Drinking Water
DOI:
https://doi.org/10.31580/pjmls.v7i2.3024Keywords:
Barkhan, Contamination, Isolation, Pathogenic, WaterAbstract
Water contamination with pathogenic microorganisms is one of the serious threats to human health, particularly in developing countries. In Pakistan, due to a lack of awareness about water-borne diseases and poor infrastructure water-borne diseases are common. Additionally, contamination of surface freshwater sources increases the frequency of waterborne disease outbreaks such as diarrhea, cholera, typhoid fever, intestinal infections, and jaundice. Therefore, the purpose of this present work was to study the quality of water in District Barkhan, Quetta Pakistan, which included identification and bacteriological characterization of antibiotic-resistant bacteria found in drinking water. A total of 500 drinking water samples were randomly collected from district Barkhan for analysis of pathogenic bacteria. Out of 500 drinking water samples, 334 (66.8%) were found contaminated with pathogenic bacteria where the prevalence of Salmonella typhi was 28%, followed by E. coli (22.4%) and P. aeruginosa (16.4%) respectively. According to our result, all S.typhi isolates were highly resistant to Ampicillin (95%), Chloramphenicol (90%), Ceftriaxone (85%), Gentamicin (85%), Sulfamethoxazole/ Trimethoprim (80%), E. coli isolates were resistant against Ampicillin (90%) followed by Ceftriaxone (85%), Chloramphenicol (80%), Azithromycin (75%) and Sulfamethoxazole/ Trimethoprim (70%), while P.aeruginosa isolates were found resistance against Ampicillin (100%), Ceftriaxone (95%), Chloramphenicol (90%), Azithromycin (75%) and Sulfamethoxazole/ Trimethoprim (70%), and while all pathogenic isolates were highly sensitive to Imipenem. The study concluded that continuous screening and treatment of water sources is essential for managing and preventing infectious diseases caused by pathogenic microorganisms. Therefore, prompt and consistent bacteriology research is needed to address the crisis caused by poor water quality.
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