Prevalence, Risk Factors, and Associated Sub-Clinical Aspects of Hepatitis A, B And C in Ethnic Groups of Panjgur District, Balochistan

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Published: Jun 30, 2023
DOI: https://doi.org/10.31580/pjmls.v6i2.2743
Keywords:
Hepatitis, Hygiene Prevalence, Panjgur, Risk factors, Unsterilized medical equipment

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Shahbaz Nazeer
Department of Zoology, University of Balochistan, Quetta, Pakistan
Asim Iqbal
Department of Zoology, University of Balochistan, Quetta, Pakistan
Mir Chakar Baloch
Department of BZoology, University of Balochistan, Quetta, Pakistan
Balach Khan
Department of Zoology, University of Balochistan, Quetta, Pakistan
Muhammad Ismail
Department of Zoology, University of Balochistan, Quetta, Pakistan
Basharat Iqbal
Department of Zoology, University of Balochistan, Quetta, Pakistan
Mahrukh Naseem
Department of Zoology, University of Balochistan, Quetta, Pakistan

Abstract

Hepatitis is a severe health matter and this study was designed at examining the occurrence of HAV, HBV and HCV specifically in major ethnic groups (Brahui, Baloch, Pashtun, punjabi Sindhi) living in District Panjgur with prior concentration given to the associated risk factors and sub-clinical features. During the study, the overall prevalence was high in males 32.77 % (370/1129) than females 27.63 % (312/1129).  Out of total 1129 studied cases, 229 (20.28%) were found to be hepatitis A patients, 375 (33.21%) individuals were suffering from HBV and 78 (6.90%) were suffering from HCV infection. Group-I (1–20 years), Group-II (21–40 years), and Group-III (41–60 years) were used to categorize all the affected people.  Infection rates were greatest in age group II (21–40 years). Similar to this, it was found that the majority of the patients had inadequate hygiene. The use of unsterilized medical and dental equipment, accidents, blood transfusions, and unsafe sexual contact were identified as the main risk factors for the spread of viral hepatitis. Fever, muscular pain, jaundice, dark urine and abdominal pain were the most commonly occurred sub-clinical features.


 

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How to Cite
Shahbaz Nazeer, Asim Iqbal, Mir Chakar Baloch, Balach Khan, Muhammad Ismail, Basharat Iqbal, & Mahrukh Naseem. (2023). Prevalence, Risk Factors, and Associated Sub-Clinical Aspects of Hepatitis A, B And C in Ethnic Groups of Panjgur District, Balochistan. Pak-Euro Journal of Medical and Life Sciences, 6(2), 55–62. https://doi.org/10.31580/pjmls.v6i2.2743
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Vol. 6 No. 2 (2023): April-June
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Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Shahbaz Nazeer, Department of Zoology, University of Balochistan, Quetta, Pakistan

Hepatitis is a severe health matter and this study was designed at examining the occurrence of HAV, HBV and HCV specifically in major ethnic groups (Brahui, Baloch, Pashtun, punjabi Sindhi) living in District Panjgur with prior concentration given to the associated risk factors and sub-clinical features. During the study, the overall prevalence was high in males 32.77 % (370/1129) than females 27.63 % (312/1129).  Out of total 1129 studied cases, 229 (20.28%) were found to be hepatitis A patients, 375 (33.21%) individuals were suffering from HBV and 78 (6.90%) were suffering from HCV infection. Group-I (1–20 years), Group-II (21–40 years), and Group-III (41–60 years) were used to categorize all the affected people.  Infection rates were greatest in age group II (21–40 years). Similar to this, it was found that the majority of the patients had inadequate hygiene. The use of unsterilized medical and dental equipment, accidents, blood transfusions, and unsafe sexual contact were identified as the main risk factors for the spread of viral hepatitis. Fever, muscular pain, jaundice, dark urine and abdominal pain were the most commonly occurred sub-clinical features.<br />

Asim Iqbal, Department of Zoology, University of Balochistan, Quetta, Pakistan

Hepatitis is a severe health matter and this study was designed at examining the occurrence of HAV, HBV and HCV specifically in major ethnic groups (Brahui, Baloch, Pashtun, punjabi Sindhi) living in District Panjgur with prior concentration given to the associated risk factors and sub-clinical features. During the study, the overall prevalence was high in males 32.77 % (370/1129) than females 27.63 % (312/1129).  Out of total 1129 studied cases, 229 (20.28%) were found to be hepatitis A patients, 375 (33.21%) individuals were suffering from HBV and 78 (6.90%) were suffering from HCV infection. Group-I (1–20 years), Group-II (21–40 years), and Group-III (41–60 years) were used to categorize all the affected people.  Infection rates were greatest in age group II (21–40 years). Similar to this, it was found that the majority of the patients had inadequate hygiene. The use of unsterilized medical and dental equipment, accidents, blood transfusions, and unsafe sexual contact were identified as the main risk factors for the spread of viral hepatitis. Fever, muscular pain, jaundice, dark urine and abdominal pain were the most commonly occurred sub-clinical features.<br />

Mir Chakar Baloch, Department of BZoology, University of Balochistan, Quetta, Pakistan

Hepatitis is a severe health matter and this study was designed at examining the occurrence of HAV, HBV and HCV specifically in major ethnic groups (Brahui, Baloch, Pashtun, punjabi Sindhi) living in District Panjgur with prior concentration given to the associated risk factors and sub-clinical features. During the study, the overall prevalence was high in males 32.77 % (370/1129) than females 27.63 % (312/1129).  Out of total 1129 studied cases, 229 (20.28%) were found to be hepatitis A patients, 375 (33.21%) individuals were suffering from HBV and 78 (6.90%) were suffering from HCV infection. Group-I (1–20 years), Group-II (21–40 years), and Group-III (41–60 years) were used to categorize all the affected people.  Infection rates were greatest in age group II (21–40 years). Similar to this, it was found that the majority of the patients had inadequate hygiene. The use of unsterilized medical and dental equipment, accidents, blood transfusions, and unsafe sexual contact were identified as the main risk factors for the spread of viral hepatitis. Fever, muscular pain, jaundice, dark urine and abdominal pain were the most commonly occurred sub-clinical features.<br />

Muhammad Ismail, Department of Zoology, University of Balochistan, Quetta, Pakistan

Hepatitis is a severe health matter and this study was designed at examining the occurrence of HAV, HBV and HCV specifically in major ethnic groups (Brahui, Baloch, Pashtun, punjabi Sindhi) living in District Panjgur with prior concentration given to the associated risk factors and sub-clinical features. During the study, the overall prevalence was high in males 32.77 % (370/1129) than females 27.63 % (312/1129).  Out of total 1129 studied cases, 229 (20.28%) were found to be hepatitis A patients, 375 (33.21%) individuals were suffering from HBV and 78 (6.90%) were suffering from HCV infection. Group-I (1–20 years), Group-II (21–40 years), and Group-III (41–60 years) were used to categorize all the affected people.  Infection rates were greatest in age group II (21–40 years). Similar to this, it was found that the majority of the patients had inadequate hygiene. The use of unsterilized medical and dental equipment, accidents, blood transfusions, and unsafe sexual contact were identified as the main risk factors for the spread of viral hepatitis. Fever, muscular pain, jaundice, dark urine and abdominal pain were the most commonly occurred sub-clinical features.<br />

Basharat Iqbal, Department of Zoology, University of Balochistan, Quetta, Pakistan

Hepatitis is a severe health matter and this study was designed at examining the occurrence of HAV, HBV and HCV specifically in major ethnic groups (Brahui, Baloch, Pashtun, punjabi Sindhi) living in District Panjgur with prior concentration given to the associated risk factors and sub-clinical features. During the study, the overall prevalence was high in males 32.77 % (370/1129) than females 27.63 % (312/1129).  Out of total 1129 studied cases, 229 (20.28%) were found to be hepatitis A patients, 375 (33.21%) individuals were suffering from HBV and 78 (6.90%) were suffering from HCV infection. Group-I (1–20 years), Group-II (21–40 years), and Group-III (41–60 years) were used to categorize all the affected people.  Infection rates were greatest in age group II (21–40 years). Similar to this, it was found that the majority of the patients had inadequate hygiene. The use of unsterilized medical and dental equipment, accidents, blood transfusions, and unsafe sexual contact were identified as the main risk factors for the spread of viral hepatitis. Fever, muscular pain, jaundice, dark urine and abdominal pain were the most commonly occurred sub-clinical features.<br />

Mahrukh Naseem, Department of Zoology, University of Balochistan, Quetta, Pakistan

Hepatitis is a severe health matter and this study was designed at examining the occurrence of HAV, HBV and HCV specifically in major ethnic groups (Brahui, Baloch, Pashtun, punjabi Sindhi) living in District Panjgur with prior concentration given to the associated risk factors and sub-clinical features. During the study, the overall prevalence was high in males 32.77 % (370/1129) than females 27.63 % (312/1129).  Out of total 1129 studied cases, 229 (20.28%) were found to be hepatitis A patients, 375 (33.21%) individuals were suffering from HBV and 78 (6.90%) were suffering from HCV infection. Group-I (1–20 years), Group-II (21–40 years), and Group-III (41–60 years) were used to categorize all the affected people.  Infection rates were greatest in age group II (21–40 years). Similar to this, it was found that the majority of the patients had inadequate hygiene. The use of unsterilized medical and dental equipment, accidents, blood transfusions, and unsafe sexual contact were identified as the main risk factors for the spread of viral hepatitis. Fever, muscular pain, jaundice, dark urine and abdominal pain were the most commonly occurred sub-clinical features.<br />

References

Kumar S, Banik A. Feed and Feeding Management for Sustainable Growth and Health of Fish in Varying Climatic Conditions. Outlook of Climate Change and Fish Nutrition: Springer; 2023:207-31.

Lee S-M. Apparent digestibility coefficients of various feed ingredients for juvenile and grower rockfish (Sebastes schlegeli). Aquaculture. 2002;207(1-2):79-95.

Kowdley KV, Wang CC, Welch S, Roberts H, Brosgart CL. Prevalence of chronic hepatitis B among foreign‐born persons living in the United States by country of origin. Hepatology. 2012;56(2):422-33.

Li J, Fan J-G. Characteristics and mechanism of liver injury in 2019 coronavirus disease. Journal of clinical and translational hepatology. 2020;8(1):13.

Zeng D-Y, Li J-M, Lin S, Dong X, You J, Xing Q-Q, et al. Global burden of acute viral hepatitis and its association with socioeconomic development status, 1990–2019. Journal of hepatology. 2021;75(3):547-56.

Maitha GM. Effects of Hepatitis B Virus Co-Infection on Immune Bio-Markers among Hiv Infected Patients Attending Comprehensive Care Clinics in Makueni County: JKUAT-COHES; 2023.

Tesfu MA, Belay NB, Habtemariam TT. Co-infection of HIV or HCV among HBsAg positive delivering mothers and its associated factors in governmental hospitals in Addis Ababa, Ethiopia: A cross-sectional study. Plos one. 2022;17(8):e0273300.

Asrani SK, Devarbhavi H, Eaton J, Kamath PS. Burden of liver diseases in the world. Journal of hepatology. 2019;70(1):151-71.

Tani J, Morishita A, Sakamoto T, Takuma K, Nakahara M, Fujita K, et al. Simple scoring system for prediction of hepatocellular carcinoma occurrence after hepatitis C virus eradication by direct‑acting antiviral treatment: All Kagawa Liver Disease Group Study. Oncology Letters. 2020;19(3):2205-12.

Liang LY, Wong VW-S, Toyoda H, Tse Y-K, Yip TC-F, Yuen BW-Y, et al. Serum hepatitis B core-related antigen predicts hepatocellular carcinoma in hepatitis B e antigen-negative patients. Journal of Gastroenterology. 2020;55:899-908.

Manon M, Hossain M. Food and feeding habit of Cyprinus carpio var. specularis. Journal of Science Foundation. 2011;9(1-2):163-9.

Ortiz E, Scanlon B, Mullens A, Durham J. Effectiveness of interventions for hepatitis B and C: a systematic review of vaccination, screening, health promotion and linkage to care within higher income countries. Journal of community health. 2020;45:201-18.

Khalid GG, Kyaw KWY, Bousquet C, Auat R, Donchuk D, Trickey A, et al. From risk to care: the hepatitis C screening and diagnostic cascade in a primary health care clinic in Karachi, Pakistan—a cohort study. International Health. 2020;12(1):19-27.

Ali T, Cunningham N. Conducting Research with People: Hepatitis C and Intensive Engagement with High-Risk Occupational Groups in Karachi, Pakistan. Global Handbook of Health Promotion Research, Vol 1: Mapping Health Promotion Research: Springer; 2022:127-36.

Nawaz R, Shakoor H, Shahid M, Ahad A, Sabri S, Ajmal A, et al. Prevalence of Hepatitis B and C, Tuberculosis, and Human Immune Deficiency Virus among injection drug users of Punjab, Pakistan-A cross sectional study. Journal of University College of Medicine and Dentistry. 2022;1(2).

Aslam I, Manzoor U, Bano S, Shahzad U, Qureshi S, Azhar T. Prevalence of Hepatitis C in pregnant patients visiting a Tertiary Care Hospital in Faisalabad. The Professional Medical Journal. 2020;27(12):2696-702.

Iqbal M, Rakhia A, Raza FA, Ambreen A, Anwar O. Prevalence and Vaccination Status of Hepatitis B among Healthcare Workers in Allied Hospital of Faisalabad: A Cross-Sectional Study, 2017-18. Journal of Occupational Health and Epidemiology. 2019;8(4):185-9.

Mudasar M, Meraj M, Hamid M, Khaskhili MS, Akhter N, Javed S. An epidemiological study for seroprevalence of transfusion transmissible infections among blood donors in Faisalabad, Pakistan. Rawal Medical Journal. 2020;45(3):531-.

Khan MI, Kalsoom F, Batool F, Kazmi A, Zahra Qua BM, Ali R, et al. Undiagnosed hepatitis B and C virus infection at a teaching hospital in Rawalpindi. Journal of Pure and Applied Microbiology. 2020;14(2):1279-86.

Rizwan A. Frequency of Hepatitis-B & C in Patients Undergoing Ocular Surgery in Rawalpindi. Ophthalmology. 2019;17(3):119.

Farooq M, Ahmad N, Saleem S. Prevalence of the HCV infection and age or gender related association in HCV-positive patients from general population of Lahore Pakistan. Pakistan Armed Forces Medical Journal. 2019;69(4):905-10.

Amir A, Azhar N, Shahbaz U, Ali SA, Ullah H, Mushtaq Q, et al. Prevalence of HBV, HCV, and its Co-Infection during Pregnancy in Lahore, Pakistan. Journal of Pharmaceutical Negative Results. 2023:9003-10.

Ismail M, Naseem M, Khan B, Baloch MC. Study on the Prevalence, Risk Factors and Clinical Aspects of Hepatitis A And B in Different Ethnic Groups of Quetta District. Pak-Euro Journal of Medical and Life Sciences. 2023;6(1):31-8.

Latif A, Sabir S, Iram S, Gul P, Yousafzai A. Hematological And Clinical Analysis of Hepatitis B Patients from Quetta, Pakistan. Pak-Euro Journal of Medical and Life Sciences. 2022;5(2):275-82.

Jahan G, Jahan N, Rungta S, Ahmad A. Seroprevalence and risk factors of hepatitis B and C infections among pregnant women. International Journal of Research in Medical Sciences. 2020;8(5):1718-23.

Sivakrishnan S, Pharm M. Liver disease overview. World Journal of Pharmacy and Pharmaceutical Sciences. 2019;8(1):1385-95.

Dike-Ndudim JN, Amadi OC, Ndubueze CW, Nwosu DC. Detection and prevalence of Hepatitis B and C among the residents of Umuaka Community, Njaba LGA, Imo State, Nigeria. GSC Advanced Research and Reviews. 2022;10(1):042-6.

Mehmood S, Raza H, Abid F, Saeed N, Rehman HM, Javed S, et al. National prevalence rate of hepatitis B and C in Pakistan and its risk factors. Journal of Public Health. 2020;28:751-64.

Alghamdi S, Dablool AS, Al-Abdullah N. Hepatitis B Seroprevalence and Consequences in Khyber Pakhtunkhwa Peshawar, Pakistan. Egyptian Academic Journal of Biological Sciences C, Physiology and Molecular Biology. 2023;15(1):295-304.

Merzah MA, Mohammed AAA-LG, Al-Aaragi ANH, Salim M. Epidemiology of Viral Hepatitis from 2007 to 2016 in Karbala Governorate, Iraq. Journal of research in health sciences. 2019;19(2):e00445.

Udoh DI, Siedoma BT, Eyo A-OA. Seroprevalence of positive cases of hepatitis A, B and C infections among subjects in two riverine communities in Akwa Ibom State, Nigeria. Brazilian Journal of Health and Biomedical Sciences. 2022;21(2):111-20.

Obaid HM, Hameed BH. Viral hepatitis incidence among vaccinated and non-vaccinated individuals in Kirkuk city, Iraq. 2019.

Khan MA. Comparative prevalence of different types of viral hepatitis in the district Dera Ismail Khan, Khyber Pakhtunkhwa, Pakistan. Egyptian Liver Journal. 2022;12(1):40.

Shaz S, Ullah N, Rafique I. Prevalence of Hepatitis B and C in District Dir Upper, Khyber Pakhtunkhwa, Pakistan. Glob J Clin Virol. 2019;4(1):8-18.

Al-Shami HZ, Al-Mutawakal ZAM, Al-Kholani AIM, Al-Haimi MA, Al-Haddad AM, Ahmed RA, et al. Prevalence of Hepatitis A virus, Hepatitis B virus, and Hepatitis C virus, among patients with hepatic jaundice in Sana’a city, Yemen: A hospital based study. Pharmaceutical Research. 2021;6(6):12-7.

Kalra P, John A, Jaleel R, Simon EG, Babji S, Joseph A. Prevalence of past hepatitis A infection among Crohn’s patients and controls–An examination of the ‘hygiene hypothesis’, and the need for hepatitis A vaccination. Tropical Doctor. 2021;51(2):193-7.

Kayesh MEH, Kohara M, Tsukiyama-Kohara K. Epidemiology and Risk Factors for Acute Viral Hepatitis in Bangladesh: An Overview. Microorganisms. 2022;10(11):2266.

Acikgoz A, Cimrin D, Kizildag S, Esen N, Balci P, Sayiner AA. Hepatitis A, B and C seropositivity among first-year healthcare students in western Turkey: a seroprevalence study. BMC Infectious Diseases. 2020;20:1-8.

Sharma CM, Gupta S, Aggarwal B, Chaudhary P. Acute viral hepatitis in children: a prospective hospital based study. International Journal of Contemporary Pediatrics. 2020;7(8):1681.

Palewar MS, Joshi S, Choudhary G, Das R, Sadafale A, Karyakarte R. Prevalence of Hepatitis A virus (HAV) and Hepatitis E virus (HEV) in patients presenting with acute viral hepatitis: A 3-year retrospective study at a tertiary care Hospital in Western India. Journal of Family Medicine and Primary Care. 2022;11(6):2437-41.

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