Evaluation of Genetic Lineage of Hazara Sub-Tribes Through Short Tandem Repeats (STRs)

Main Article Content

Masooma
Irfan Shahzad Sheikh
Niamatullah Kakar
Heera Batool

Abstract

The Hazaras counting over 7 million, are primarily found in central Afghanistan and southwest Pakistan's Quetta contributing about 0.09 percent of Pakistan's overall population, Hazaras are one of the unique but minor ethnicities. Studies have been done on Hazara people through Short Tandem Repeats (STRs) but there is no any study on the genetic lineage of Hazara sub-tribes. Short Tandem Repeats (STRs) have a key role in the forensic study these days. These short tandem repeats (STRs) contain short nucleotide repeats which vary from individual to individual and can be used in fingerprinting in modern days. There is a wide usage of STRs such as genetic lineage, historical background, paternity testing, finding culprits in harassment and theft cases because small amount of DNA is required to process the study. The Hazara population, with their distinctive genetic profile, offers a unique opportunity to investigate the genetic lineage of sub-tribes within this minority group. Understanding the genetic diversity and ancestry of Hazara sub-tribes can shed light on their migration patterns and historical origins. By employing Short Tandem Repeats (STRs), which exhibit high variability and can be easily analyzed, this study aims to unravel the intricate genetic landscape of Hazara sub-tribes in Quetta, Pakistan. The findings from this research will not only contribute to the scientific knowledge of Hazara genetics but also have implications for forensic investigations, population studies, and paternity testing. Furthermore, the utilization of STRs in this study highlights the importance of this molecular tool in unraveling the complex genetic identities of human populations. Through a comprehensive analysis of genetic lineage using STRs, this study will provide valuable insights into the genetic diversity and sub-tribal structure of the Hazara population in Quetta.

Article Details

How to Cite
Masooma, Irfan Shahzad Sheikh, Niamatullah Kakar, & Heera Batool. (2023). Evaluation of Genetic Lineage of Hazara Sub-Tribes Through Short Tandem Repeats (STRs). Pak-Euro Journal of Medical and Life Sciences, 6(2), 85–90. https://doi.org/10.31580/pjmls.v6i2.2169
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Author Biographies

Masooma, Center for Advanced Studies in Vaccinology and Biotechnology, (CASVAB), UoB, Quetta

The Hazaras counting over 7 million, are primarily found in central Afghanistan and southwest Pakistan's Quetta contributing about 0.09 percent of Pakistan's overall population, Hazaras are one of the unique but minor ethnicities. Studies have been done on Hazara people through Short Tandem Repeats (STRs) but there is no any study on the genetic lineage of Hazara sub-tribes. Short Tandem Repeats (STRs) have a key role in the forensic study these days. These short tandem repeats (STRs) contain short nucleotide repeats which vary from individual to individual and can be used in fingerprinting in modern days. There is a wide usage of STRs such as genetic lineage, historical background, paternity testing, finding culprits in harassment and theft cases because small amount of DNA is required to process the study. The Hazara population, with their distinctive genetic profile, offers a unique opportunity to investigate the genetic lineage of sub-tribes within this minority group. Understanding the genetic diversity and ancestry of Hazara sub-tribes can shed light on their migration patterns and historical origins. By employing Short Tandem Repeats (STRs), which exhibit high variability and can be easily analyzed, this study aims to unravel the intricate genetic landscape of Hazara sub-tribes in Quetta, Pakistan. The findings from this research will not only contribute to the scientific knowledge of Hazara genetics but also have implications for forensic investigations, population studies, and paternity testing. Furthermore, the utilization of STRs in this study highlights the importance of this molecular tool in unraveling the complex genetic identities of human populations. Through a comprehensive analysis of genetic lineage using STRs, this study will provide valuable insights into the genetic diversity and sub-tribal structure of the Hazara population in Quetta.

Irfan Shahzad Sheikh, Center for Advanced Studies in Vaccinology and Biotechnology, (CASVAB), UoB, Quetta

The Hazaras counting over 7 million, are primarily found in central Afghanistan and southwest Pakistan's Quetta contributing about 0.09 percent of Pakistan's overall population, Hazaras are one of the unique but minor ethnicities. Studies have been done on Hazara people through Short Tandem Repeats (STRs) but there is no any study on the genetic lineage of Hazara sub-tribes. Short Tandem Repeats (STRs) have a key role in the forensic study these days. These short tandem repeats (STRs) contain short nucleotide repeats which vary from individual to individual and can be used in fingerprinting in modern days. There is a wide usage of STRs such as genetic lineage, historical background, paternity testing, finding culprits in harassment and theft cases because small amount of DNA is required to process the study. The Hazara population, with their distinctive genetic profile, offers a unique opportunity to investigate the genetic lineage of sub-tribes within this minority group. Understanding the genetic diversity and ancestry of Hazara sub-tribes can shed light on their migration patterns and historical origins. By employing Short Tandem Repeats (STRs), which exhibit high variability and can be easily analyzed, this study aims to unravel the intricate genetic landscape of Hazara sub-tribes in Quetta, Pakistan. The findings from this research will not only contribute to the scientific knowledge of Hazara genetics but also have implications for forensic investigations, population studies, and paternity testing. Furthermore, the utilization of STRs in this study highlights the importance of this molecular tool in unraveling the complex genetic identities of human populations. Through a comprehensive analysis of genetic lineage using STRs, this study will provide valuable insights into the genetic diversity and sub-tribal structure of the Hazara population in Quetta.

Niamatullah Kakar, Department of Natural and Basic Sciences, University of Turbat, Kech, Pakistan

The Hazaras counting over 7 million, are primarily found in central Afghanistan and southwest Pakistan's Quetta contributing about 0.09 percent of Pakistan's overall population, Hazaras are one of the unique but minor ethnicities. Studies have been done on Hazara people through Short Tandem Repeats (STRs) but there is no any study on the genetic lineage of Hazara sub-tribes. Short Tandem Repeats (STRs) have a key role in the forensic study these days. These short tandem repeats (STRs) contain short nucleotide repeats which vary from individual to individual and can be used in fingerprinting in modern days. There is a wide usage of STRs such as genetic lineage, historical background, paternity testing, finding culprits in harassment and theft cases because small amount of DNA is required to process the study. The Hazara population, with their distinctive genetic profile, offers a unique opportunity to investigate the genetic lineage of sub-tribes within this minority group. Understanding the genetic diversity and ancestry of Hazara sub-tribes can shed light on their migration patterns and historical origins. By employing Short Tandem Repeats (STRs), which exhibit high variability and can be easily analyzed, this study aims to unravel the intricate genetic landscape of Hazara sub-tribes in Quetta, Pakistan. The findings from this research will not only contribute to the scientific knowledge of Hazara genetics but also have implications for forensic investigations, population studies, and paternity testing. Furthermore, the utilization of STRs in this study highlights the importance of this molecular tool in unraveling the complex genetic identities of human populations. Through a comprehensive analysis of genetic lineage using STRs, this study will provide valuable insights into the genetic diversity and sub-tribal structure of the Hazara population in Quetta.

Heera Batool, Center for Advanced Studies in Vaccinology and Biotechnology, (CASVAB), UoB, Quetta

The Hazaras counting over 7 million, are primarily found in central Afghanistan and southwest Pakistan's Quetta contributing about 0.09 percent of Pakistan's overall population, Hazaras are one of the unique but minor ethnicities. Studies have been done on Hazara people through Short Tandem Repeats (STRs) but there is no any study on the genetic lineage of Hazara sub-tribes. Short Tandem Repeats (STRs) have a key role in the forensic study these days. These short tandem repeats (STRs) contain short nucleotide repeats which vary from individual to individual and can be used in fingerprinting in modern days. There is a wide usage of STRs such as genetic lineage, historical background, paternity testing, finding culprits in harassment and theft cases because small amount of DNA is required to process the study. The Hazara population, with their distinctive genetic profile, offers a unique opportunity to investigate the genetic lineage of sub-tribes within this minority group. Understanding the genetic diversity and ancestry of Hazara sub-tribes can shed light on their migration patterns and historical origins. By employing Short Tandem Repeats (STRs), which exhibit high variability and can be easily analyzed, this study aims to unravel the intricate genetic landscape of Hazara sub-tribes in Quetta, Pakistan. The findings from this research will not only contribute to the scientific knowledge of Hazara genetics but also have implications for forensic investigations, population studies, and paternity testing. Furthermore, the utilization of STRs in this study highlights the importance of this molecular tool in unraveling the complex genetic identities of human populations. Through a comprehensive analysis of genetic lineage using STRs, this study will provide valuable insights into the genetic diversity and sub-tribal structure of the Hazara population in Quetta.

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