Functional and Phytochemical potential of Berberis
DOI:
https://doi.org/10.31580/pjmls.v4iSpecial%20Is.1755Keywords:
Berberidaceae, Baluchistanamine, Anti- cancer activity, anti-rheumaticAbstract
The plant is wide source for possible medications and in the ongoing years there has been a good understanding about the significance of medicinal plants. Medications from the plants are effectively accessible, more affordable, protected, and productive without causing harm unlike allopathic medicines. Different phytochemicals are extracted in the form of primary and secondary metabolites from these plants. These phytochemicals mainly comprise of alkaloids, glycosides, polyphenols and terpenes. These extracts have a wide range of activities like analgesic, sedative, laxative, anti-inflammatory, antioxidant, antibacterial and neuropharmacological activities. Berberis baluchistanica plant locally called as Karoskai (Pashtu), Zrolg and Korae (Balochi), which belongs to the family Berberidaceae potentially contains phytochemicals with antioxidant activities. These phytochemicals are selected to discover its uses as an antioxidant. The genus Berberis (Berberdaceae) entails of almost 500 species occurring in many areas of central and southern Europe, the northeastern parts of the United States and in South Asia including the north of Pakistan. Berberis is applicable for wound healing. It is also indicated in some studies that Berberis species are useful for treatment of insomnia, lungs diseases, unease of gastrointestinal tract (GIT), liver disorder and urinary incontinence. It can also be used as anti-rheumatic, antifungal, antipyretic, and antibacterial infection. Due to the presence Berberine, oxy acanthine, Berberine and palmatine play the vital role as phytochemical. Cancer prevention agent capability of fifty percent aqueous ethanolic root extract of B. aristata was investigated. Its effect on antioxidant enzymes of liver was studied in diabetic rats. The root extract of B. aristata can possibly reduce oxidative stress. Antioxidant capability of dried parts of B. aristata were explored in fluid and methanolic separate and berberine, against CCl4 actuated liver injury.
References
1. Abbasi, M. A., Naqvi, S. S. H., Rehman, A. ur, & Tareen, R. B. (2013). Berberis Baluchistanica: Assessment of Natural Antioxidants to Reprieve from Oxidative Stress. International Research Journal of Pharmacy, 4(5), 101–105.
2. Ahmed, S., Shuaib, M., Ali, K., Ali, S., & Hussain, F. (2017). Evaluation of different parts of Berberis lyceum and their biological activities: a review. Pure and Applied Biology (PAB), 6(3), 897-907.
3. Akhtar, M. S., Jabeen, Q., Bashir, S., Malik, M. N., Karim, S., Mushtaq, M. N., ... & Ahsan, H. (2014). Possible mechanism of cardiac depressant activity of Berberis orthobotrys roots in isolated rabbit heart. Acta poloniae pharmaceutica, 71(4), 667-675.
4. Akhtar, M. S., Sajid, S. M., Akhtar, M. S., & Ahmad, M. (2008). Hypoglycaemic effect of Berberis aristata roots, aqueous and methanolic extracts in normal and alloxan-diabetic rabbits. Pharmacologyonline, 2, 845-856.
5. Alamzeb, M., Omer, M., Ur-Rashid, M., Raza, M., Ali, S., Khan, B., & Ullah, A. (2018). NMR, novel pharmacological and in silico docking studies of oxyacanthine and tetrandrine: bisbenzylisoquinoline alkaloids isolated from Berberis glaucocarpa roots. Journal of analytical methods in chemistry, 2018.
6. Ali, S., Igoli, J., Clements, C., Alamzeb, M., Shah, S. Q., Ferro, V. A., ... & Khan, M. R. (2013). Anti-diabetic and antimicrobial activities of fractions and compounds isolated from Berberis brevissima Jafri and Berberis parkeriana Schneid. Bangladesh Journal of Pharmacology, 8(3), 336-342.
7. Alvarez, M. A., Eraso, N. F., Pitta-Alvarez, S. I., & Marconi, P. L. (2009). Two-stage culture for producing berberine by cell suspension and shoot cultures of Berberis buxifolia Lam. Biotechnology letters, 31(3), 457-463.
8. Andola, H. C. (2012). Genus Berberis and berberine HPLC: an overview. Journal of Biologically Active Products from Nature, 2(5), 256-264.
9. Andola, H. C., Gaira, K. S., Pandey, A., Bhatt, I. D., & Rawal, R. S. (2019). Influence of habitat characteristics and altitude on berberine content in Berberis jaeschkeana CK Schneid. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 89(3), 967-972.
10. Anis, K. V., Rajeshkumar, N. V., & Kuttan, R. (2001). Inhibition of chemical carcinogenesis by berberine in rats and mice. Journal of Pharmacy and Pharmacology, 53(5), 763-768.
11. Anna, H., Zden?k, N., Pérez Daniel, I., Šárka, Š., Martina, H., Ji?í, K., ... & Lubomír, O. (August, 2015). Alkaloids from Berberis vulgaris and their biological activities connected to Alzheimer's disease. [Poster Presentation]. Planta Medica, London.
12. Anwar, M. A., Tabassam, S., Gulfraz, M., Sheeraz Ahmad, M., Raja, G. K., & Arshad, M. (2020). Isolation of Oxyberberine and ?-Sitosterol from Berberis lycium Royle Root Bark Extract and In Vitro Cytotoxicity against Liver and Lung Cancer Cell Lines. Evidence-Based Complementary and Alternative Medicine, 2020.
13. Batiha, G. E. S., Magdy Beshbishy, A., Adeyemi, O. S., Nadwa, E. H., Alkazmi, L. M., Elkelish, A. A., & Igarashi, I. (2020). Phytochemical screening and antiprotozoal effects of the methanolic Berberis vulgaris and acetonic Rhus coriaria extracts. Molecules, 25(3), 550.
14. Bhatt, V., Kumar, M. M., & Selvam, P. S. (2018). Antimicrobial effect of ajwain seed ethanolic extract against food borne pathogenic bacteria. International Food Research Journal, 25(3), 908-912.
15. Chanda, S., Parekh, J., Vaghasiya, Y., Dave, R., Baravalia, Y., & Nair, R. (2015). Medicinal plants-from traditional use to toxicity assessment: a review. International Journal of Pharmaceutical Sciences and Research, 6(7), 2652.
16. Chandel, S., Bagai, U., Semwal, R. B., & Semwal, D. K. (2015). Antiplasmodial activity of aqueous extract of Berberis aristata roots against Plasmodium berghei-infected BALB/c mice. Pharmaceutical Biology, 53(12), 1735-1740.
17. Das, S., Das, M. K., Mazumder, P. M., Das, S., & Basu, S. P. (2009). Cytotoxic activity of methanolic extract of Berberis aristata DC on colon cancer. Global Journal of Pharmacology, 3(3), 137-140.
18. Derosa, G., Maffioli, P., & Cicero, A. F. (2012). Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials. Expert opinion on biological therapy, 12(8), 1113-1124.
19. Desai, S. D., Desai, D. G., & Kaur, H. (2009). Saponins and their biological activities. Pharma Times, 41(3), 13-16.
20. Dong, Y., Chen, Y. T., Yang, Y. X., Zhou, X. J., Dai, S. J., Tong, J. F., ... & Li, C. (2016). Metabolomics study of type 2 diabetes mellitus and the antidiabetic effect of berberine in zucker diabetic fatty rats using Uplc?ESI?Hdms. Phytotherapy Research, 30(5), 823-828.
21. Dong, Z. Y., Zeng, Q. H., Wei, L., Guo, X., Sun, Y., Meng, F. C., ... & Chen, M. (2020). Berberisides AD: three novel prenylated benzoic acid derivatives and a clerodane glycoside from Berberis tsarica aherndt. Natural Product Research, 1-6.
22. Florence, A. R., Sukumaran, S., Joselin, J., Brintha, T. S., & Jeeva, S. (2015). Phytochemical screening of selected medicinal plants of the family Lythraceae. Biosci Discov, 6(2), 73-82.
23. Grishkovets, V. I. (1999). Alkaloids of some species of the genus Berberis introduced into the Crimea. Chemistry of natural compounds, 35(2), 223-224.
24. Grosvenor, P. W., Supriono, A., & Gray, D. O. (1995). Medicinal plants from Riau Province, Sumatra, Indonesia. Part 2: antibacterial and antifungal activity. Journal of ethnopharmacology, 45(2), 97-111.
25. Gupta, S. K., Agarwal, R., Srivastava, S., Agarwal, P., Agrawal, S. S., Saxena, R., & Galpalli, N. (2008). The anti-inflammatory effects of Curcuma longa and Berberis aristata in endotoxin-induced uveitis in rabbits. Investigative ophthalmology & visual science, 49(9), 4036-4040.
26. Gupte, S. (1975). Use of berberine in treatment of giardiasis. American Journal of Diseases of Children, 129(7), 866-866.
27. Hostalkova, A., Marikova, J., Opletal, L., Korabecny, J., Hulcova, D., Kunes, J., ... & Andrisano, V. (2019). Isoquinoline alkaloids from Berberis vulgaris as potential lead compounds for the treatment of Alzheimer’s disease. Journal of natural products, 82(2), 239-248.
28. Hussain, M. A., Khan, M. Q., Habib, T., & Hussain, N. (2011). Antimicronbial activity of the crude root extract of Berberis lycium Royle. Advances in Environmental Biology, 5(4), 585-588.
29. Imenshahidi, M., & Hosseinzadeh, H. (2016). Berberis vulgaris and berberine: an update review. Phytotherapy research, 30(11), 1745-1764.
30. Irshad, A. H., Pervaiz, A. H., Abrar, Y. B., Fahelboum, I., & Awen, B. Z. (2013). Antibacterial activity of Berberis lycium root extract. Trakia J Sci, 1, 88-90.
31. Jang, M. H., Piao, X. L., Kim, J. M., Kwon, S. W., & Park, J. H. (2008). Inhibition of cholinesterase and amyloid?? aggregation by resveratrol oligomers from Vitis amurensis. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 22(4), 544-549.
32. Joshi, P. V., Shirkhedkar, A. A., Prakash, K., & Maheshwari, V. L. (2011). Antidiarrheal activity, chemical and toxicity profile of Berberis aristata. Pharmaceutical biology, 49(1), 94-100.
33. Khan, I., Najeebullah, S., Ali, M., & Shinwari, Z. K. (2016). Phytopharmacological and ethnomedicinal uses of the Genus Berberis (Berberidaceae): A review. Tropical Journal of Pharmaceutical Research, 15(9), 2047-2057.
34. Kim, K. H., Choi, S. U., Kim, C. S., & Lee, K. R. (2012). Cytotoxic Steroids from the Trunk of Berberis koreana. Bioscience, biotechnology, and biochemistry, 76(4), 825-827.
35. Kong, W., Wei, J., Abidi, P., Lin, M., Inaba, S., Li, C., ... & Wang, S. (2004). Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nature medicine, 10(12), 1344-1351.
36. Küpeli, E., Ko?ar, M., Ye?ilada, E., & Ba?er, K. H. C. (2002). A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life sciences, 72(6), 645-657.
37. Lamichhane, B., Adhikari, S., Shrestha, P., & Shrestha, B. G. (2014). Study of phytochemical, antioxidant, antimicrobial and anticancer activity of Berberis aristata. Journal of Tropical Life Science, 4(1), 01-07.
38. Lan, J., Zhao, Y., Dong, F., Yan, Z., Zheng, W., Fan, J., & Sun, G. (2015). Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. Journal of ethnopharmacology, 161, 69-81.
39. Malik, T. A., Kamili, A. N., Chishti, M. Z., Tanveer, S., Ahad, S., & Johri, R. K. (2014). In vivo anticoccidial activity of berberine [18, 5, 6-dihydro-9, 10-dimethoxybenzo (g)-1, 3-benzodioxolo (5, 6-a) quinolizinium]–an isoquinoline alkaloid present in the root bark of Berberis lycium. Phytomedicine, 21(5), 663-669.
40. Meliani, N., Dib, M. E. A., Allali, H., & Tabti, B. (2011). Hypoglycaemic effect of Berberis vulgaris L. in normal and streptozotocin-induced diabetic rats. Asian Pacific journal of tropical biomedicine, 1(6), 468.
41. Mithraja, M. J., Marimuthu, J., Mahesh, M., Paul, Z. M., & Jeeva, S. (2011). Phytochemical studies on Azolla pinnata R. Br., Marsilea minuta L. and Salvinia molesta Mitch. Asian Pacific Journal of Tropical Biomedicine, 1(1), S26-S29.
42. Mladin, P., Mladin, G., Oprea, E., & Nicola, C. (2011). Variability of the anthocyanins and tannins in berries of some Lonicera caerulea var. kamchatica, Aronia melanocarpa and Berberis thunbergii var. atropurpurea genotypes. Scientific Papers of the Research Institute for Fruit Growing, Pitesti, Romania, 27.
43. Mokhber-Dezfuli, N., Saeidnia, S., Gohari, A. R., & Kurepaz-Mahmoodabadi, M. (2014). Phytochemistry and pharmacology of berberis species. Pharmacognosy reviews, 8(15), 8.
44. Musumeci, R., Speciale, A., Costanzo, R., Annino, A., Ragusa, S., Rapisarda, A., ... & Iauk, L. (2003). Berberis aetnensis C. Presl. extracts: antimicrobial properties and interaction with ciprofloxacin. International journal of antimicrobial agents, 22(1), 48-53.
45. Nakamoto, K., Sadamori, S., & Hamada, T. (1990). Effects of crude drugs and berberine hydrochloride on the activities of fungi. The Journal of prosthetic dentistry, 64(6), 691-694.
46. Okunade, A. L., Hufford, C. D., Richardson, M. D., Peterson, J. R., & Clark, A. M. (1994). Antimicrobial properties of alkaloids from Xanthorhiza simplicissima. Journal of pharmaceutical sciences, 83(3), 404-406.
47. Parekh, J., & Chanda, S. (2011). Antibacterial and phytochemical studies on twelve species of Indian medicinal plants. African Journal of Biomedical Research, 10(2), 175–181. https://doi.org/10.4314/ajbr.v10i2.50624
48. Patel Pineshkumar, S., Gajera, V., Lambole, V., & Shah, D. P. Phytochemistry and Pharmacological Activities of Berberis aristata: An Overview.
49. Potdar, D., Hirwani, R. R., & Dhulap, S. (2012). Phyto-chemical and pharmacological applications of Berberis aristata. Fitoterapia, 83(5), 817-830.
50. Rashmi, Rajasekaran, A., Rekha, P., & Singh, Y. P. (2009). Quantitative estimation of berberine in roots of different provenances of Berberis aristata DC by HPLC and study of their antifungal properties. Pharmacognosy Magazine, 5(20), 355–358. https://doi.org/10.4103/0973-1296.58566
51. Rahman, A., & Ansari, A. A. (2011). Alkaloids of Berberis +aristata-isolation of aromoline and oxyberberine. Journal of The Chemical Society of Pakistan, 5(4), 283.
52. Sack, R. B., & Froehlich, J. L. (1982). Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins. Infection and immunity, 35(2), 471-475.
53. Saki, K., Eftekhari, Z., Naghdi, N., & Bahmani, M. (2016). Berberis vulgaris as an antihypertensive drug; berbamine and oxycontin antihypertensive active ingredients. Journal of Preventive Epidemiology, 1(2), e18.
54. Saravanakumar, T., Venkatasubramanian, P., Vasanthi, N. S., & Manonmani, E. (2014). Antimicrobial potential of Daruharidra (Berberis aristata DC) against the pathogens causing eye infection. International Journal of Green Pharmacy (IJGP), 8(3).
55. Sharma, R. S., Mishra, V., Singh, R., Seth, N., & Babu, C. R. (2008). Antifungal activity of some Himalayan medicinal plants and cultivated ornamental species. Fitoterapia, 79(7-8), 589-591.
56. Singh, N. V., Azmi, S., Maurya, S., Singh, U. P., Jha, R. N., & Pandey, V. B. (2003). Two plant alkaloids isolated from Corydalis longipes as potential antifungal agents. Folia microbiologica, 48(5), 605-609.
57. Srivastava, S., Srivastava, M., Misra, A., Pandey, G., & Rawat, A. (2015). A review on biological and chemical diversity in Berberis (Berberidaceae). EXCLI journal, 14, 247.
58. Suttee, A., Rana, S., Kaura, G., Sharma, S., Singh, M., Sharma, A., & Arora, D. (2011). Pharmacognostical and Phytochemical Evaluation of Caesalpinia bonduc. Canadian Journal of Pure and Applied Sciences, 5(3), 1631-1636.
59. Tang, L. Q., Wei, W., Chen, L. M., & Liu, S. (2006). Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats. Journal of Ethnopharmacology, 108(1), 109-115.
60. Ullah, S., Gul, J., Gul, F., Khan, S., & Sher, J. (2018). Antifungal and phytochemical screening of selected medicinal plants of Malamjaba, Swat, Pakistan. The Pharma Innovation, 7(5, Part C), 176.
61. Vaghasiya, Y., Dave, R., & Chanda, S. (2011). Phytochemical analysis of some medicinal plants from western region of India. Research journal of medicinal plant, 5(5), 567-576.
2. Ahmed, S., Shuaib, M., Ali, K., Ali, S., & Hussain, F. (2017). Evaluation of different parts of Berberis lyceum and their biological activities: a review. Pure and Applied Biology (PAB), 6(3), 897-907.
3. Akhtar, M. S., Jabeen, Q., Bashir, S., Malik, M. N., Karim, S., Mushtaq, M. N., ... & Ahsan, H. (2014). Possible mechanism of cardiac depressant activity of Berberis orthobotrys roots in isolated rabbit heart. Acta poloniae pharmaceutica, 71(4), 667-675.
4. Akhtar, M. S., Sajid, S. M., Akhtar, M. S., & Ahmad, M. (2008). Hypoglycaemic effect of Berberis aristata roots, aqueous and methanolic extracts in normal and alloxan-diabetic rabbits. Pharmacologyonline, 2, 845-856.
5. Alamzeb, M., Omer, M., Ur-Rashid, M., Raza, M., Ali, S., Khan, B., & Ullah, A. (2018). NMR, novel pharmacological and in silico docking studies of oxyacanthine and tetrandrine: bisbenzylisoquinoline alkaloids isolated from Berberis glaucocarpa roots. Journal of analytical methods in chemistry, 2018.
6. Ali, S., Igoli, J., Clements, C., Alamzeb, M., Shah, S. Q., Ferro, V. A., ... & Khan, M. R. (2013). Anti-diabetic and antimicrobial activities of fractions and compounds isolated from Berberis brevissima Jafri and Berberis parkeriana Schneid. Bangladesh Journal of Pharmacology, 8(3), 336-342.
7. Alvarez, M. A., Eraso, N. F., Pitta-Alvarez, S. I., & Marconi, P. L. (2009). Two-stage culture for producing berberine by cell suspension and shoot cultures of Berberis buxifolia Lam. Biotechnology letters, 31(3), 457-463.
8. Andola, H. C. (2012). Genus Berberis and berberine HPLC: an overview. Journal of Biologically Active Products from Nature, 2(5), 256-264.
9. Andola, H. C., Gaira, K. S., Pandey, A., Bhatt, I. D., & Rawal, R. S. (2019). Influence of habitat characteristics and altitude on berberine content in Berberis jaeschkeana CK Schneid. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences, 89(3), 967-972.
10. Anis, K. V., Rajeshkumar, N. V., & Kuttan, R. (2001). Inhibition of chemical carcinogenesis by berberine in rats and mice. Journal of Pharmacy and Pharmacology, 53(5), 763-768.
11. Anna, H., Zden?k, N., Pérez Daniel, I., Šárka, Š., Martina, H., Ji?í, K., ... & Lubomír, O. (August, 2015). Alkaloids from Berberis vulgaris and their biological activities connected to Alzheimer's disease. [Poster Presentation]. Planta Medica, London.
12. Anwar, M. A., Tabassam, S., Gulfraz, M., Sheeraz Ahmad, M., Raja, G. K., & Arshad, M. (2020). Isolation of Oxyberberine and ?-Sitosterol from Berberis lycium Royle Root Bark Extract and In Vitro Cytotoxicity against Liver and Lung Cancer Cell Lines. Evidence-Based Complementary and Alternative Medicine, 2020.
13. Batiha, G. E. S., Magdy Beshbishy, A., Adeyemi, O. S., Nadwa, E. H., Alkazmi, L. M., Elkelish, A. A., & Igarashi, I. (2020). Phytochemical screening and antiprotozoal effects of the methanolic Berberis vulgaris and acetonic Rhus coriaria extracts. Molecules, 25(3), 550.
14. Bhatt, V., Kumar, M. M., & Selvam, P. S. (2018). Antimicrobial effect of ajwain seed ethanolic extract against food borne pathogenic bacteria. International Food Research Journal, 25(3), 908-912.
15. Chanda, S., Parekh, J., Vaghasiya, Y., Dave, R., Baravalia, Y., & Nair, R. (2015). Medicinal plants-from traditional use to toxicity assessment: a review. International Journal of Pharmaceutical Sciences and Research, 6(7), 2652.
16. Chandel, S., Bagai, U., Semwal, R. B., & Semwal, D. K. (2015). Antiplasmodial activity of aqueous extract of Berberis aristata roots against Plasmodium berghei-infected BALB/c mice. Pharmaceutical Biology, 53(12), 1735-1740.
17. Das, S., Das, M. K., Mazumder, P. M., Das, S., & Basu, S. P. (2009). Cytotoxic activity of methanolic extract of Berberis aristata DC on colon cancer. Global Journal of Pharmacology, 3(3), 137-140.
18. Derosa, G., Maffioli, P., & Cicero, A. F. (2012). Berberine on metabolic and cardiovascular risk factors: an analysis from preclinical evidences to clinical trials. Expert opinion on biological therapy, 12(8), 1113-1124.
19. Desai, S. D., Desai, D. G., & Kaur, H. (2009). Saponins and their biological activities. Pharma Times, 41(3), 13-16.
20. Dong, Y., Chen, Y. T., Yang, Y. X., Zhou, X. J., Dai, S. J., Tong, J. F., ... & Li, C. (2016). Metabolomics study of type 2 diabetes mellitus and the antidiabetic effect of berberine in zucker diabetic fatty rats using Uplc?ESI?Hdms. Phytotherapy Research, 30(5), 823-828.
21. Dong, Z. Y., Zeng, Q. H., Wei, L., Guo, X., Sun, Y., Meng, F. C., ... & Chen, M. (2020). Berberisides AD: three novel prenylated benzoic acid derivatives and a clerodane glycoside from Berberis tsarica aherndt. Natural Product Research, 1-6.
22. Florence, A. R., Sukumaran, S., Joselin, J., Brintha, T. S., & Jeeva, S. (2015). Phytochemical screening of selected medicinal plants of the family Lythraceae. Biosci Discov, 6(2), 73-82.
23. Grishkovets, V. I. (1999). Alkaloids of some species of the genus Berberis introduced into the Crimea. Chemistry of natural compounds, 35(2), 223-224.
24. Grosvenor, P. W., Supriono, A., & Gray, D. O. (1995). Medicinal plants from Riau Province, Sumatra, Indonesia. Part 2: antibacterial and antifungal activity. Journal of ethnopharmacology, 45(2), 97-111.
25. Gupta, S. K., Agarwal, R., Srivastava, S., Agarwal, P., Agrawal, S. S., Saxena, R., & Galpalli, N. (2008). The anti-inflammatory effects of Curcuma longa and Berberis aristata in endotoxin-induced uveitis in rabbits. Investigative ophthalmology & visual science, 49(9), 4036-4040.
26. Gupte, S. (1975). Use of berberine in treatment of giardiasis. American Journal of Diseases of Children, 129(7), 866-866.
27. Hostalkova, A., Marikova, J., Opletal, L., Korabecny, J., Hulcova, D., Kunes, J., ... & Andrisano, V. (2019). Isoquinoline alkaloids from Berberis vulgaris as potential lead compounds for the treatment of Alzheimer’s disease. Journal of natural products, 82(2), 239-248.
28. Hussain, M. A., Khan, M. Q., Habib, T., & Hussain, N. (2011). Antimicronbial activity of the crude root extract of Berberis lycium Royle. Advances in Environmental Biology, 5(4), 585-588.
29. Imenshahidi, M., & Hosseinzadeh, H. (2016). Berberis vulgaris and berberine: an update review. Phytotherapy research, 30(11), 1745-1764.
30. Irshad, A. H., Pervaiz, A. H., Abrar, Y. B., Fahelboum, I., & Awen, B. Z. (2013). Antibacterial activity of Berberis lycium root extract. Trakia J Sci, 1, 88-90.
31. Jang, M. H., Piao, X. L., Kim, J. M., Kwon, S. W., & Park, J. H. (2008). Inhibition of cholinesterase and amyloid?? aggregation by resveratrol oligomers from Vitis amurensis. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 22(4), 544-549.
32. Joshi, P. V., Shirkhedkar, A. A., Prakash, K., & Maheshwari, V. L. (2011). Antidiarrheal activity, chemical and toxicity profile of Berberis aristata. Pharmaceutical biology, 49(1), 94-100.
33. Khan, I., Najeebullah, S., Ali, M., & Shinwari, Z. K. (2016). Phytopharmacological and ethnomedicinal uses of the Genus Berberis (Berberidaceae): A review. Tropical Journal of Pharmaceutical Research, 15(9), 2047-2057.
34. Kim, K. H., Choi, S. U., Kim, C. S., & Lee, K. R. (2012). Cytotoxic Steroids from the Trunk of Berberis koreana. Bioscience, biotechnology, and biochemistry, 76(4), 825-827.
35. Kong, W., Wei, J., Abidi, P., Lin, M., Inaba, S., Li, C., ... & Wang, S. (2004). Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nature medicine, 10(12), 1344-1351.
36. Küpeli, E., Ko?ar, M., Ye?ilada, E., & Ba?er, K. H. C. (2002). A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. Life sciences, 72(6), 645-657.
37. Lamichhane, B., Adhikari, S., Shrestha, P., & Shrestha, B. G. (2014). Study of phytochemical, antioxidant, antimicrobial and anticancer activity of Berberis aristata. Journal of Tropical Life Science, 4(1), 01-07.
38. Lan, J., Zhao, Y., Dong, F., Yan, Z., Zheng, W., Fan, J., & Sun, G. (2015). Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension. Journal of ethnopharmacology, 161, 69-81.
39. Malik, T. A., Kamili, A. N., Chishti, M. Z., Tanveer, S., Ahad, S., & Johri, R. K. (2014). In vivo anticoccidial activity of berberine [18, 5, 6-dihydro-9, 10-dimethoxybenzo (g)-1, 3-benzodioxolo (5, 6-a) quinolizinium]–an isoquinoline alkaloid present in the root bark of Berberis lycium. Phytomedicine, 21(5), 663-669.
40. Meliani, N., Dib, M. E. A., Allali, H., & Tabti, B. (2011). Hypoglycaemic effect of Berberis vulgaris L. in normal and streptozotocin-induced diabetic rats. Asian Pacific journal of tropical biomedicine, 1(6), 468.
41. Mithraja, M. J., Marimuthu, J., Mahesh, M., Paul, Z. M., & Jeeva, S. (2011). Phytochemical studies on Azolla pinnata R. Br., Marsilea minuta L. and Salvinia molesta Mitch. Asian Pacific Journal of Tropical Biomedicine, 1(1), S26-S29.
42. Mladin, P., Mladin, G., Oprea, E., & Nicola, C. (2011). Variability of the anthocyanins and tannins in berries of some Lonicera caerulea var. kamchatica, Aronia melanocarpa and Berberis thunbergii var. atropurpurea genotypes. Scientific Papers of the Research Institute for Fruit Growing, Pitesti, Romania, 27.
43. Mokhber-Dezfuli, N., Saeidnia, S., Gohari, A. R., & Kurepaz-Mahmoodabadi, M. (2014). Phytochemistry and pharmacology of berberis species. Pharmacognosy reviews, 8(15), 8.
44. Musumeci, R., Speciale, A., Costanzo, R., Annino, A., Ragusa, S., Rapisarda, A., ... & Iauk, L. (2003). Berberis aetnensis C. Presl. extracts: antimicrobial properties and interaction with ciprofloxacin. International journal of antimicrobial agents, 22(1), 48-53.
45. Nakamoto, K., Sadamori, S., & Hamada, T. (1990). Effects of crude drugs and berberine hydrochloride on the activities of fungi. The Journal of prosthetic dentistry, 64(6), 691-694.
46. Okunade, A. L., Hufford, C. D., Richardson, M. D., Peterson, J. R., & Clark, A. M. (1994). Antimicrobial properties of alkaloids from Xanthorhiza simplicissima. Journal of pharmaceutical sciences, 83(3), 404-406.
47. Parekh, J., & Chanda, S. (2011). Antibacterial and phytochemical studies on twelve species of Indian medicinal plants. African Journal of Biomedical Research, 10(2), 175–181. https://doi.org/10.4314/ajbr.v10i2.50624
48. Patel Pineshkumar, S., Gajera, V., Lambole, V., & Shah, D. P. Phytochemistry and Pharmacological Activities of Berberis aristata: An Overview.
49. Potdar, D., Hirwani, R. R., & Dhulap, S. (2012). Phyto-chemical and pharmacological applications of Berberis aristata. Fitoterapia, 83(5), 817-830.
50. Rashmi, Rajasekaran, A., Rekha, P., & Singh, Y. P. (2009). Quantitative estimation of berberine in roots of different provenances of Berberis aristata DC by HPLC and study of their antifungal properties. Pharmacognosy Magazine, 5(20), 355–358. https://doi.org/10.4103/0973-1296.58566
51. Rahman, A., & Ansari, A. A. (2011). Alkaloids of Berberis +aristata-isolation of aromoline and oxyberberine. Journal of The Chemical Society of Pakistan, 5(4), 283.
52. Sack, R. B., & Froehlich, J. L. (1982). Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins. Infection and immunity, 35(2), 471-475.
53. Saki, K., Eftekhari, Z., Naghdi, N., & Bahmani, M. (2016). Berberis vulgaris as an antihypertensive drug; berbamine and oxycontin antihypertensive active ingredients. Journal of Preventive Epidemiology, 1(2), e18.
54. Saravanakumar, T., Venkatasubramanian, P., Vasanthi, N. S., & Manonmani, E. (2014). Antimicrobial potential of Daruharidra (Berberis aristata DC) against the pathogens causing eye infection. International Journal of Green Pharmacy (IJGP), 8(3).
55. Sharma, R. S., Mishra, V., Singh, R., Seth, N., & Babu, C. R. (2008). Antifungal activity of some Himalayan medicinal plants and cultivated ornamental species. Fitoterapia, 79(7-8), 589-591.
56. Singh, N. V., Azmi, S., Maurya, S., Singh, U. P., Jha, R. N., & Pandey, V. B. (2003). Two plant alkaloids isolated from Corydalis longipes as potential antifungal agents. Folia microbiologica, 48(5), 605-609.
57. Srivastava, S., Srivastava, M., Misra, A., Pandey, G., & Rawat, A. (2015). A review on biological and chemical diversity in Berberis (Berberidaceae). EXCLI journal, 14, 247.
58. Suttee, A., Rana, S., Kaura, G., Sharma, S., Singh, M., Sharma, A., & Arora, D. (2011). Pharmacognostical and Phytochemical Evaluation of Caesalpinia bonduc. Canadian Journal of Pure and Applied Sciences, 5(3), 1631-1636.
59. Tang, L. Q., Wei, W., Chen, L. M., & Liu, S. (2006). Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats. Journal of Ethnopharmacology, 108(1), 109-115.
60. Ullah, S., Gul, J., Gul, F., Khan, S., & Sher, J. (2018). Antifungal and phytochemical screening of selected medicinal plants of Malamjaba, Swat, Pakistan. The Pharma Innovation, 7(5, Part C), 176.
61. Vaghasiya, Y., Dave, R., & Chanda, S. (2011). Phytochemical analysis of some medicinal plants from western region of India. Research journal of medicinal plant, 5(5), 567-576.
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2021-08-25
