In this study hybridization of chemistry learning activities in secondary school was carried out through the development of flipped classroom models. Activity hybridization is the composition of learning inside and outside the classroom with appropriate supporting modules and learning videos. Variations in the composition of learning activities inside and outside the classroom are done through a flipped classroom model that is integrated with the Problem-Based Learning (PBL) and Inquiry models. The research was conducted by the development research method from Richey and Klein, with the implementation stage using experimental strategies, 2x2 treatment by level design and nonequivalent control group design. The results of the implementation show that on the topic of the Reaction Rate, the hybridization composition of activities inside and outside the classroom with flipped classroom-PBL models can improve scientific literacy and flipped classroom models-inquiry can improve student learning outcomes in secondary school.
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